Tuesday, June 11, 2013

Oral Contraceptive Pill

Contraceptives:

This section includes combined oestrogen progestrogen oral contraceptive and progestrogen only contraceptives.



Conbined Oral Contraceptives:


Oral Contraceptives containing an oestrogen and a progestrogen are the most effective preparations for general use.


The dosage regimen for combined oral contraceptives is usually 1 tablet daily for 21 days followed by a 7 days interval.


Dose of Conbined Oral Contraceptives:

1.  Levonorgestel 0.15mg , Ethyl Estradiao 0.03mg per tablet.
     28's tablet- 1 tablet daily for 21 days starting on 1st day on menstruation.

2.  Norgestimate 0.25mg, Ethiyl estradiol 0.003mg per tablet.
     21's tablet- 1 tablet daily for 21 days beginning on day 1 of menstrual cycle followed by a tablet interval
    of 7  days.

Use:  used as contraception & other menstrual problems.


Side Effect :

- Nausea
- Vomiting
- Headache
- Breast tenderness
- Change body weight
- Changes in libido
- Depression
- Hypertension-Impairment of liver function
- Benign hepatic tumors
- Reduced menstrual loss
- Spotting in early cycles
- Amonorrhoea


 Indication:  Contraception( control menopausal & menstrual symptoms)

Cautions:

- Diabetes
- Hypertension
- Cardiac or renal diseases
- Migraine
- Depression
- Asthama
- Uterine fibromyomatar 
- Lactation
- Risk of arterial thrombosis associated with oral contraception is increased with age and aggraveted by smoking and obesity.


Progestogen Only Contraceptives:

When oestrogens are contra-indicated progestogen only  preparations may offer a suitable alternative but have a higher failure rate them combined preparations. Oral preparations are start on the 1st day of the cycle and taken every day.


How  it Work

Dose:

1.  Allyoestrenal 5mg per tablet.
    Continue until at least 1 month after the end of critical period.

    Premature lobour , according to individual up to 40mg per tablet daily have been used.

Indication: Threatened or habitual abortion, failure on nidation where due to lack of progesterone threatened pre-mature labour.

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